• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val29-Ala248
Catalog #BH7-RM173
Price
Regular price $31500
Regular price Sale price $31500
/
Size
Avantor VWR Fisher Scientific

Order by 4pm ET for delivery on:

Rat B7-H3 (2Ig) /CD276 Protein (BH7-RM173) Summary

Product Description

 Recombinant Rat B7-H3 (2Ig) /CD276 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Val29-Ala248.

Product Background

 B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Rat B7-H3 (2Ig) /CD276 Protein (BH7-RM173) Specifications/Details

Protein
 B7-H3 (2Ig)
Synonyms
 B7H3; B7-H3; CD276; PSEC0249;-UNQ309; PRO352; B7 homolog 3; CD276
Accession
Species
 Rat
Biotinylated
 no
Amino Acid Range
 Val29-Ala248
Molecular Weight
 The protein has a predicted MW of 25.40 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Rat B7-H3 (2Ig) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Rat B7-H3 (2Ig) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Rat B7-H3 (2Ig) is greater than 95% as determined by SEC-HPLC. The purity of Rat B7-H3 (2Ig) is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...