Rat FcRn Protein (FRN-RM101)
Catalog: FRN-RM101
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| Product Description | Recombinant Rat FcRn Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala23-Ser298 (FCGRT) and Ile21-Met119 (B2M). |
Product Background |
The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer. |
Product Category |
Recombinant Protein |
Target |
FcRn |
Gene/Protein ID |
P13599(FCGRT)&P07151(B2M) |
Species |
Rat |
Exact Sequence |
Ala23-Ser298(FCGRT) & Ile21-Met119(B2M) |
| Molecular Weight | The protein has a predicted MW of 32.60 kDa (FCGRT) and 11.63 kDa (B2M). Due to glycosylation, the protein migrates to 45-60 kDa (FCGRT) and 13-15 kDa (B2M) based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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The purity of Rat FcRn is greater than 95% as determined by SEC-HPLC. |
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Rat FcRn on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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