Name: Rat IL-22R alpha 1 Protein (ILR-RM222)
Brand: KactusBio
SKU: ILR-RM222-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Rat IL-22R alpha 1, hFc Tag with the EC50 of 36.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: His16-Ala228

Catalog #ILR-RM222

Size

100UG

500UG

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Rat IL-22R alpha 1 Protein (ILR-RM222) Summary

Product Description	Recombinant Rat IL-22R alpha 1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains His16-Ala228.
Product Background	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Rat IL-22R alpha 1 Protein (ILR-RM222) Specifications/Details

Protein	IL-22R alpha 1
Synonyms	IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11
Accession	NP_001178798.1
Species	Rat
Biotinylated	no
Amino Acid Range	His16-Ala228
Molecular Weight	The protein has a predicted MW of 51.08 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Rat IL-22R alpha 1, hFc Tag with the EC50 of 36.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS, 100m L-Arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Rat IL-22R alpha 1, hFc Tag with the EC50 of 36.6ng/ml determined by ELISA (QC Test).
	Rat IL-22R alpha 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Rat IL-22R alpha 1, hFc Tag on ProA-Biosensor can bind Human IL-22, His Tag with an affinity constant of 0.31 uM as determined in BLI assay (Gator® Prime).
	The purity of Rat IL-22R alpha 1 is greater than 95% as determined by SEC-HPLC.