Rat PLAU/uPA Protein (PLA-RM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
  • Activity: The affinity constant of 4.31 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Gly20-Phe432

Catalog: PLA-RM101

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Product Description Recombinant Rat PLAU/uPA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly20-Phe432.

Product Background

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.

Product Category

Recombinant Protein

Target

PLAU/uPA
Accession

Species

Rat

Amino Acid Range

Gly20-Phe432
Molecular Weight The protein has a predicted MW of 46.91 kDa. The protein migrates to 30-35 kDa based on Tris-Bis PAGE result.

Activity

The affinity constant of 4.31 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human uPAR, hFc Tag captured on CM5 Chip via Protein A can bind Rat PLAU, His Tag with an affinity constant of 4.31 uM as determined in SPR assay (Biacore T200).
The purity of Rat PLAU is greater than 90% as determined by SEC-HPLC.
Rat PLAU on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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