Rat PLAU/uPA Protein (PLA-RM101)
Catalog: PLA-RM101
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Product Description | Recombinant Rat PLAU/uPA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly20-Phe432. |
Product Background |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC. |
Product Category |
Recombinant Protein |
Target |
PLAU/uPA |
Gene/Protein ID |
NP_037217.3 |
Species |
Rat |
Exact Sequence |
Gly20-Phe432 |
Molecular Weight | The protein has a predicted MW of 46.91 kDa. The protein migrates to 30-35 kDa based on Tris-Bis PAGE result. |
Activity |
The affinity constant of 4.31 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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