Product Description |
Recombinant Rat PLAU/uPA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly20-Phe432. |
Product Background |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC. |
Product Category |
Recombinant Protein |
Target |
PLAU/uPA |
Synonyms |
PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD |
Accession |
|
Species |
Rat |
Biotinylated |
no |
Amino Acid Range |
Gly20-Phe432 |
Molecular Weight |
The protein has a predicted MW of 46.91 kDa. The protein migrates to 30-35 kDa based on Bis-Tris PAGE result. |
Activity |
The affinity constant of 4.31 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human uPAR, hFc Tag captured on CM5 Chip via Protein A can bind Rat PLAU, His Tag with an affinity constant of 4.31 uM as determined in SPR assay (Biacore T200). |
|
|
Rat PLAU on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Rat PLAU is greater than 90% as determined by SEC-HPLC. |
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