Name: Rat TIGIT Protein (TIG-RM310)
Brand: KactusBio
SKU: TIG-RM310-100UG
Price: 347.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-mFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Mouse CD155, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Rat TIGIT, mFc Tag with the EC50 of 23.1ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala17-Gln136

Catalog #TIG-RM310

Size

100UG

500UG

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Product Description	Recombinant Rat TIGIT Protein is expressed from HEK293 with mFc (IgG2a) tag at the C-terminus.It contains Ala17-Gln136.
Product Background	TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins.IGIT is expressed at low levels on peripheral memory and regulatory CD4 T-cells and NK cells and is up-regulated following activation of these cells.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	TIGIT
Synonyms	TIGIT; VSIG9; VSTM3; WUCAM
Accession	D3ZTQ2
Species	Rat
Biotinylated	no
Amino Acid Range	Ala17-Gln136
Molecular Weight	The protein has a predicted MW of 39.47 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Mouse CD155, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Rat TIGIT, mFc Tag with the EC50 of 23.1ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-mFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Mouse CD155, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Rat TIGIT, mFc Tag with the EC50 of 23.1ng/ml determined by ELISA.
	Rat TIGIT on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Mouse CD155, His Tag on Anti-His-Biosensor can bind Rat TIGIT, mFc Tag with an affinity constant of 6.93 nM as determined in BLI assay (Gator® Prime).
	The purity of Rat TIGIT is greater than 95% as determined by SEC-HPLC.