Regular price
$346.50
Order by 4pm ET for delivery on:
Rhesus macaque CDH17/Cadherin 17 Protein, Ultra Low Endotoxin (CDH-RM117-UL) Summary
Product Description |
Recombinant Rhesus macaque CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Thr784. |
Product Background |
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
Product Category |
Recombinant Protein / Antibody discovery / ADC targets |
Rhesus macaque CDH17/Cadherin 17 Protein, Ultra Low Endotoxin (CDH-RM117-UL) Specifications/Details
Protein |
CDH17/Cadherin 17 |
Synonyms |
Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024 |
Accession |
|
Species |
Rhesus macaque |
Biotinylated |
no |
Amino Acid Range |
Gln23-Thr784 |
Molecular Weight |
The protein has a predicted MW of 85.60 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Rhesus macaque CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.2ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 0.01 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Rhesus macaque CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.2ng/ml determined by ELISA. |
|
|
Rhesus macaque CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%. |
|
|
Loaded Anti-CDH17 Antibody, hFc-Avi Tag on ProA-Biosensor can bind Rhesus macaque CDH17, His Tag with an affinity constant of 7.54 nM as determined in BLI assay . |
|
|
The purity of Rhesus macaque CDH17 is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
