Rhesus macaque Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-RM1V6)
Catalog: ITG-RM1V6
Order now get it on
| Product Description | Recombinant Rhesus macaque Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe31-Pro993 (ITGAV) acidic tail and Gly22-Asn707 (ITGB6) basic tail. |
Product Background |
ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. |
Product Category |
Recombinant Protein |
Target |
Integrin alpha V beta 6 (ITGAV&ITGB6) |
| Synonyms | ITGAV&ITGB6；Integrin alpha V beta 6 |
| Accession | |
Species |
Rhesus macaque |
Amino Acid Range |
Phe31-Pro993(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail |
| Molecular Weight | The protein has a predicted MW of 112.1 kDa (ITGAV) and 79 kDa (ITGB6). Due to glycosylation, the protein migrates to 90-140 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Rhesus macaque ITGAV&ITGB6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-alpha-V Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Immobilized Rhesus macaque ITGAV&ITGB6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-alpha-V Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. |
|
|
The purity of Rhesus macaque ITGAV&ITGB6 is greater than 95% as determined by SEC-HPLC. |
|
|
Rhesus macaque ITGAV&ITGB6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
You may also be interested in
View more associated products