SARS-CoV-2 3CLpro/3C-like Protease Protein (COV-VE0CL)

  • Express System: E.coli
  • Product Tag: No Tag
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser1-Gln306

Catalog: COV-VE0CL


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Product Description Recombinant SARS-CoV-2 3CLpro/3C-like Protease Protein is expressed from E.coli without tag.It contains Ser1-Gln306.

Product Background

3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase.

Product Category

Recombinant Protein


3CLpro/3C-like Protease
Synonyms 3C-like protease; 3CL Protease; 3CL-Mpro; 3CL Pro; COVID-19; M Proteinase; Mpro



Amino Acid Range

Molecular Weight The protein has a predicted MW of 33.8 kDa same as Tris-Bis PAGE result.

Product Tag

No Tag

Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 25mM HEPES, 2.5mM DTT, 10% Glycerol (pH 7.5).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Measured by its ability to cleave a peptide substrate, MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2.The specific activity is > 5 pmol/min/ug.
The purity of SARS-CoV-2 3CLpro is greater than 95% as determined by SEC-HPLC.
SARS-CoV-2 3CLpro on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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