SARS-COV-2 NSP7&NSP8 Protein (NSP-VE178)

  • Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Amino Acid Range: Ser1-Gln83(NSP7) & Ala1-Gln198(NSP8)

Catalog: NSP-VE178

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Product Description SARS-COV-2 NSP7&NSP8 Protein is expressed from E.coil with His tag at the C-Terminus.It contains Ser1-Gln83(NSP7)&Ala1-Gln198(NSP8).

Product Background

The crystal structure of the metabolite of remdesivir (Monophosphate of GS-441524) and NSP12-NSP8-NSP7 of SARS CoV-2 virus was recently reported. The crystal structures of ADP-Ribose or AMP and NSP3 of SARS CoV-2 virus were also released, recently. The crystal structure of NSP3 of SARS CoV-2 virus as an alternative binding site of AMP or ADP-ribose to treat COVID-19.

Product Category

Recombinant Protein

Target

NSP7&NSP8
Synonyms SP7&NSP8; nsp7&nsp8
Accession

Species

SARS-CoV-2

Amino Acid Range

Ser1-Gln83(NSP7) & Ala1-Gln198(NSP8)
Molecular Weight The protein has a predicted MW of 32.8 kDa same as Tris-Bis PAGE result.

Product Tag

C-His

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM Nacl, 200mM Arginine (pH 8.2). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SARS-COV-2 NSP7&NSP8 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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