SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)
  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Glu1564-Val1880
Catalog #COV-VE1PL
Regular price $405.00
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Product Description
Recombinant SARS-COV-2 PLpro/papain-like protease Protein is expressed from E.coli with His tag at the N-Terminus.It contains Glu1564-Val1880.
Product Background
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.
Product Category
Recombinant Protein
Target
PLpro/papain-like protease
Synonyms
Replicase polyprotein 1a; pp1a; nsp1; PL2-PRO; PL-PRO; Papain-like Protease; Plpro
Accession
Species
SARS-COV-2
Biotinylated
no
Amino Acid Range
Glu1564-Val1880
Molecular Weight
The protein has a predicted MW of 39.2 kDa same as Bis-Tris PAGE result.
Product Tag
N-His
Express System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in 20mM Tris, 100mM NaCl, 10% Glycerol (pH 8.5).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
SARS-COV-2 PLpro on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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