SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)

  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Glu1564-Val1880

Catalog: COV-VE1PL

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Product Description Recombinant SARS-COV-2 PLpro/papain-like protease Protein is expressed from E.coli with His tag at the N-Terminus.It contains Glu1564-Val1880.

Product Background

The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.

Product Category

Recombinant Protein

Target

PLpro/papain-like protease

Gene/Protein ID

YP_009725299.1

Species

SARS-COV-2

Exact Sequence

Glu1564-Val1880
Molecular Weight The protein has a predicted MW of 39.2 kDa same as Tris-Bis PAGE result.

Product Tag

N-His

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22um filtered solution in 20mM Tris, 100mM NaCl, 10% Glycerol (pH 8.5).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
SARS-COV-2 PLpro on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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