Name: SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)
Brand: KactusBio
SKU: COV-VE1PL-100UG
Price: 445.5 USD
Availability: InStock

SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)

SARS-COV-2 PLpro on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: E.coli
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Glu1564-Val1880

Catalog #COV-VE1PL

Size

100UG

500UG

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Product Description	Recombinant SARS-COV-2 PLpro/papain-like protease Protein is expressed from E.coli with His tag at the N-Terminus.It contains Glu1564-Val1880.
Product Background	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.
Product Category	Recombinant Protein / Antibody discovery

Protein	PLpro/papain-like protease
Synonyms	Replicase polyprotein 1a; pp1a; nsp1; PL2-PRO; PL-PRO; Papain-like Protease; Plpro
Accession	YP_009725299.1
Species	SARS-COV-2
Biotinylated	no
Amino Acid Range	Glu1564-Val1880
Molecular Weight	The protein has a predicted MW of 39.2 kDa same as Bis-Tris PAGE result.
Product Tag	N-His
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM Tris, 100mM NaCl, 10% Glycerol (pH 8.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.