SARS-COV-2 Spike S Trimer Protein (COV-VM2SS)
SARS-COV-2 Spike S Trimer Protein (COV-VM2SS)
  • Express System: HEK293
  • Product Tag: C-monomeric hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike S (Trimer) , hFc Tag with the EC50 of 0.22ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Val16-Glu1188
Catalog #COV-VM2SS
Regular price $375.00
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Product Description

Recombinant SARS-COV-2 Spike S Trimer Protein is expressed from HEK293 with monomeric hFc tag at the C-Terminus.It contains Val16-Glu1188.

Product Background

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Product Category

Recombinant Protein / Antibody discovery

Protein

Spike S Trimer

Synonyms

S protein; Spike glycoprotein; S glycoprotein; COVID-19

Accession

Species

SARS-COV-2

Biotinylated

no

Amino Acid Range

Val16-Glu1188

Molecular Weight

The protein has a predicted MW of 158.3 kDa. Due to glycosylation, the protein migrates to 230-250 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike S (Trimer) , hFc Tag with the EC50 of 0.22ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-monomeric hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike S (Trimer) , hFc Tag with the EC50 of 0.22ug/ml determined by ELISA. Immobilized Human ACE2, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for SARS-COV-2 Spike S (Trimer) , hFc Tag with the EC50 of 0.22ug/ml determined by ELISA.
SARS-COV-2 Spike S (Trimer) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. SARS-COV-2 Spike S (Trimer) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of SARS-COV-2 Spike S (Trimer) is greater than 95% as determined by SEC-HPLC. The purity of SARS-COV-2 Spike S (Trimer) is greater than 95% as determined by SEC-HPLC.

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