• Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala2-Asn346
Catalog #ANX-HE1A1
Price
Regular price $264.00
Regular price Sale price $264.00
/
Size
Avantor VWR Fisher Scientific

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Human ANXA1 Protein (ANX-HE1A1) Summary

Product Description

 Recombinant Human ANXA1 Protein is expressed from E.coli with His tag at the C-terminus.It contains Ala2-Asn346.

Product Background

 Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance.

Human ANXA1 Protein (ANX-HE1A1) Specifications/Details

Protein
 ANXA1
Synonyms
 Annexin I; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; p35; ANX1; LPC1; Annexin A1; Annexin-1; ANXA1
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ala2-Asn346
Molecular Weight
 The protein has a predicted MW of 39.5 kDa same as Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 E.coli
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human ANXA1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ANXA1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human ANXA1 is greater than 95% as determined by SEC-HPLC. The purity of Human ANXA1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...