• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val23-Gly342
Catalog #TIM-CM101
Price
Regular price $346.50
Regular price Sale price $346.50
/
Size
Avantor VWR Fisher Scientific

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Cynomolgus TIM-1/HAVCR1 Protein (TIM-CM101) Summary

Product Description

 Recombinant Cynomolgus TIM-1/HAVCR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val23-Gly342.

Product Background

 Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation.

Cynomolgus TIM-1/HAVCR1 Protein (TIM-CM101) Specifications/Details

Protein
 TIM-1/HAVCR1
Synonyms
 HAVcr-1; KIM-1; KIM1; TIMD-1; TIMD1;TIM; TIM-1; TIM1; CD365; HAVCR1; HAVCR; HAVCR-1
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Val23-Gly342
Molecular Weight
 The protein has a predicted MW of 35.25 kDa. Due to glycosylation, the protein migrates to 100-150 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Cynomolgus TIM-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus TIM-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus TIM-1 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus TIM-1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
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