Biotinylated Human CD47 Protein (CD7-HM547B)
Biotinylated Human CD47 Protein (CD7-HM547B)
  • Express System: HEK293
  • Product Tag: C-hFc-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln19-Pro139
Catalog #CD7-HM547B
Regular price $577.50
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Biotinylated Human CD47 Protein (CD7-HM547B) Summary

Product Description

Recombinant Biotinylated Human CD47 Protein is expressed from HEK293 with hFc tag and Avi tag at the C-terminus.It contains Gln19-Pro139.

Product Background

CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Biotinylated Human CD47 Protein (CD7-HM547B) Specifications/Details

Protein
CD47
Synonyms
CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Gln19-Pro139
Molecular Weight
The protein has a predicted MW of 42.61 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-hFc-Avi
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human CD47 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human CD47 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human CD47 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human CD47 is greater than 95% as determined by SEC-HPLC.
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