Name: Biotinylated Human CD47 Protein (CD7-HM547B)
Brand: KactusBio
SKU: CD7-HM547B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human CD47 Protein (CD7-HM547B)

Express System: HEK293
Product Tag: C-hFc-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gln19-Pro139

Catalog #CD7-HM547B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human CD47 Protein is expressed from HEK293 with hFc tag and Avi tag at the C-terminus.It contains Gln19-Pro139.
Product Background	CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.
Product Category	Recombinant Protein

Target	CD47
Synonyms	CD47 glycoprotein; CD47 molecule; CD47; IAP; OA3; MER6
Accession	Q08722-1
Species	Human
Biotinylated	yes
Amino Acid Range	Gln19-Pro139
Molecular Weight	The protein has a predicted MW of 42.61 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-hFc-Avi
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Biotinylated Human CD47 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human CD47 is greater than 95% as determined by SEC-HPLC.

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