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Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein (GCC-MM401B) Summary
Product Description |
Recombinant Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Val20-Met433. |
Product Background |
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy. |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets | ADC targets |
Biotinylated Mouse GUCY2C/Guanylyl cyclase C Protein (GCC-MM401B) Specifications/Details
Protein |
GUCY2C/Guanylyl cyclase C |
Synonyms |
Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL |
Accession |
|
Species |
Mouse |
Biotinylated |
yes |
Amino Acid Range |
Val20-Met433 |
Molecular Weight |
The protein has a predicted MW of 50.01 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
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Biotinylated Mouse GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Biotinylated Mouse GUCY2C is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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