Canine GUCY2C/Guanylyl cyclase C Protein (GCC-DM101)
Canine GUCY2C/Guanylyl cyclase C Protein (GCC-DM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr21-Gln430
Catalog #GCC-DM101
Regular price $330.00
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Product Description
Recombinant Canine GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr21-Gln430.
Product Background
Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Product Category
Recombinant Protein
Target
GUCY2C/Guanylyl cyclase C
Synonyms
Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Accession
Species
Canine
Biotinylated
no
Amino Acid Range
Tyr21-Gln430
Molecular Weight
The protein has a predicted MW of 47.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Canine GUCY2C/Guanylyl cyclase C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine GUCY2C/Guanylyl cyclase C is greater than 95% as determined by SEC-HPLC.

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