Canine ROR1 Protein (ROR-DM101) Summary
Product Description |
Recombinant Canine ROR1 Protein is expressed from HEK293 with His tag at the C-Terminus; It contains Ala22-Glu477. |
Product Background |
ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1),- is a member of- the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members. |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets |
Canine ROR1 Protein (ROR-DM101) Specifications/Details
Protein |
ROR1 |
Synonyms |
ROR1; NTRKR1; dJ537F10.1 |
Accession |
|
Species |
Canine |
Biotinylated |
no |
Amino Acid Range |
Ala22-Glu477 |
Molecular Weight |
The protein has a predicted MW of 52.2 kDa. Due to glycosylation, the protein migrates to 65-68 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Canine ROR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Canine ROR1 is greater than 95% as determined by SEC-HPLC. |
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