Name: Cynomolgus B7-H3/CD276 Protein (BH7-CM173)
Brand: KactusBio
SKU: BH7-CM173-100UG
Price: 270.0 USD
Availability: InStock

Cynomolgus B7-H3/CD276 Protein (BH7-CM173)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus B7-H3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-B7-H3 Antibody, hFc Tag with the EC50 of 5.5ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Leu29-Glu465

Catalog #BH7-CM173

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus B7-H3/CD276 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu29-Glu465.
Product Background	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.
Product Category	Recombinant Protein

Target	B7-H3/CD276
Synonyms	B7H3; B7-H3; CD276; PSEC0249;-UNQ309; PRO352; B7 homolog 3; CD276
Accession	XP_015308534.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Leu29-Glu465
Molecular Weight	The protein has a predicted MW of 48.2 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus B7-H3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-B7-H3 Antibody, hFc Tag with the EC50 of 5.5ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus B7-H3, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-B7-H3 Antibody, hFc Tag with the EC50 of 5.5ng/ml determined by ELISA.
	Cynomolgus B7-H3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus B7-H3 is greater than 95% as determined by SEC-HPLC.

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