Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein (BCM-CM217)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus/Rhesus macaque BCMA, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BCMA Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Met1-Ala53

Catalog: BCM-CM217

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Product Description Recombinant Cynomolgus/Rhesus macaque BCMA/TNFRSF17 Protein is expressed from HEK293 with hFc at the C-Terminus.It contains Met1-Ala53.

Product Background

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).

Product Category

Recombinant Protein

Target

BCMA/TNFRSF17
Synonyms CD269; TNFRSF17; BCMA; BCM; TNFRSF13A

Gene/Protein ID

A0A2K5UD97/F7FFA0

Species

Cynomolgus/Rhesus macaque

Exact Sequence

Met1-Ala53
Molecular Weight The protein has a predicted MW of 31.5 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus/Rhesus macaque BCMA, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BCMA Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus/Rhesus macaque BCMA, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BCMA Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA.
Immobilized Cynomolgus APRIL (Trimer) , His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus/Rhesus macaque BCMA, hFc Tag with the EC50 of 1.9ng/ml determined by ELISA.
The purity of Cynomolgus/Rhesus macaque BCMA is greater than 95% as determined by SEC-HPLC.
Cynomolgus/Rhesus macaque BCMA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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