Cynomolgus CD46 Protein (CD4-CM146)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus CD46, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 0.67ug/ml determined by ELISA. See testing image for detail.
Exact Sequence: Cys35-Asp329

Catalog: CD4-CM146

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Cynomolgus CD46 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys35-Asp329.
Product Background	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
Product Category	Recombinant Protein

Target	CD46
Gene/Protein ID	A0A2K5WCS2
Species	Cynomolgus
Exact Sequence	Cys35-Asp329
Molecular Weight	The protein has a predicted MW of 34.05 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus CD46, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 0.67ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus CD46, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 0.67ug/ml determined by ELISA.
	The purity of Cynomolgus CD46 is greater than 95% as determined by SEC-HPLC.
	Cynomolgus CD46 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.