Name: Cynomolgus CD46 Protein (CD4-CM146)
Brand: KactusBio
SKU: CD4-CM146-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus CD46, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 0.46ug/ml determined by ELISA (QC Test).
Amino Acid Range: Cys35-Asp329

Catalog #CD4-CM146

Size

100UG

500UG

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Cynomolgus CD46 Protein (CD4-CM146) Summary

Product Description	Recombinant Cynomolgus CD46 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys35-Asp329.
Product Background	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Cynomolgus CD46 Protein (CD4-CM146) Specifications/Details

Protein	CD46
Synonyms	TLX; CD46; MCP; MIC10; AHUS2; TRA2.10
Accession	A0A2K5WCS2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Cys35-Asp329
Molecular Weight	The protein has a predicted MW of 34.05 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus CD46, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 0.46ug/ml determined by ELISA (QC Test).
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus CD46, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD46 Antibody, hFc Tag with the EC50 of 0.46ug/ml determined by ELISA (QC Test).
	Cynomolgus CD46 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus CD46 is greater than 95% as determined by SEC-HPLC.

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