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Cynomolgus EPHA2 Protein (EPH-CM2A2) Summary
Product Description |
Recombinant Cynomolgus EPHA2 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ala24-Ser534. |
Product Background |
Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; therefore, it is important to understand how EPHA2 gene (EPHA2) expression is regulated. |
Product Category |
Recombinant Protein / Antibody discovery / ADC targets |
Cynomolgus EPHA2 Protein (EPH-CM2A2) Specifications/Details
Protein |
EPHA2 |
Synonyms |
Ephrin type-A receptor 2 ; EC:2.7.10.1; EPHA2 |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Ala24-Ser534 |
Molecular Weight |
The protein has a predicted MW of 83.1 kDa. Due to glycosylation, the protein migrates to 90-100 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Cynomolgus EPHA2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Cynomolgus EPHA2 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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