Name: Cynomolgus FLT3/Flk-2 Protein (FLT-CM230)
Brand: KactusBio
SKU: FLT-CM230-100UG
Price: 346.5 USD
Availability: InStock

Cynomolgus FLT3/Flk-2 Protein (FLT-CM230)

Immobilized Human FLT3 Ligand, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FLT3, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA.

Cynomolgus FLT3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human FLT3 Ligand, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FLT3, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln28-Ser541

Catalog #FLT-CM230

Size

100UG

500UG

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Cynomolgus FLT3/Flk-2 Protein (FLT-CM230) Summary

Product Description	Recombinant Cynomolgus FLT3/Flk-2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln28-Ser541.
Product Background	The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Cynomolgus FLT3/Flk-2 Protein (FLT-CM230) Specifications/Details

Protein	FLT3/Flk-2
Synonyms	CD135; FLK2; STK-1; FLT-3
Accession	A0A2K5VQ48
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln28-Ser541
Molecular Weight	The protein has a predicted MW of 84.58 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human FLT3 Ligand, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FLT3, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human FLT3 Ligand, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FLT3, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA.
	Cynomolgus FLT3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.