Name: Cynomolgus GUCY2C/Guanylyl cyclase C Protein (GCC-CM101)
Brand: KactusBio
SKU: GCC-CM101-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus GUCY2C/Guanylyl cyclase C Protein (GCC-CM101)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus GUCY2C, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 0.68ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ser24-Gln430

Catalog #GCC-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Gln430.
Product Background	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Product Category	Recombinant Protein

Target	GUCY2C/Guanylyl cyclase C
Synonyms	Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
Accession	XP_005570270.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ser24-Gln430
Molecular Weight	The protein has a predicted MW of 47.2 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus GUCY2C, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 0.68ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus GUCY2C, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GUCY2C Antibody, hFc Tag with the EC50 of 0.68ug/ml determined by ELISA.
	Cynomolgus GUCY2C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus GUCY2C is greater than 95% as determined by SEC-HPLC.

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