|Recombinant Cynomolgus LDLR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-Gly788.
|The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles.
|LDLR; FHC; LDL R; LDL receptor; LDLCQ2; FH
|The protein has a predicted MW of 86 kDa, Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result.
|The affinity constant of 0.27 nM as determined in SPR assay (Biacore T200). See testing image for detail.
|> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
|Less than 1EU per ug by the LAL method.
|Shipped at ambient temperature.
|Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
|Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
|Stability And Storage
|Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.