Cynomolgus LDLR Protein (LDL-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 0.27 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Ala22-Gly788
Catalog #LDL-CM101
Regular price $300.00
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Product Description
Recombinant Cynomolgus LDLR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-Gly788.
Product Background
The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles.
Product Category
Recombinant Protein
Target
LDLR
Synonyms
LDLR; FHC; LDL R; LDL receptor; LDLCQ2; FH
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Ala22-Gly788
Molecular Weight
The protein has a predicted MW of 86 kDa, Due to glycosylation, the protein migrates to 115-130 kDa based on Bis-Tris PAGE result.
Activity
The affinity constant of 0.27 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Cynomolgus LDLR, His Tag immobilized on CM5 Chip can bind Cynomolgus PCSK9, His Tag with an affinity constant of 0.27 nM as determined in SPR assay (Biacore T200).
Cynomolgus LDLR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus LDLR is greater than 95% as determined by SEC-HPLC.

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