Name: Cynomolgus LILRB2/CD85d/ILT4 Protein (LIL-CM1B2)
Brand: KactusBio
SKU: LIL-CM1B2-100UG
Price: 346.5 USD
Availability: InStock

Cynomolgus LILRB2/CD85d/ILT4 Protein (LIL-CM1B2)

Cynomolgus LILRB2, His Tag immobilized on CM5 Chip can bind Cynomolgus HLA-G Complex Tetramer, His Tag with an affinity constant of 852 nM as determined in SPR assay (Biacore T200).

Cynomolgus LILRB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus LILRB2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 852 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly24-Arg457

Catalog #LIL-CM1B2

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Cynomolgus LILRB2/CD85d/ILT4 Protein (LIL-CM1B2) Summary

Product Description	Recombinant Cynomolgus LILRB2/CD85d/ILT4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly24-Arg457.
Product Background	The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Cynomolgus LILRB2/CD85d/ILT4 Protein (LIL-CM1B2) Specifications/Details

Protein	LILRB2/CD85d/ILT4
Synonyms	CD85d; ILT4; ILT-4; ILT4CD85d; LILRB2; LIR2; MIR10
Accession	XP_015297203.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gly24-Arg457
Molecular Weight	The protein has a predicted MW of 48.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 852 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Cynomolgus LILRB2, His Tag immobilized on CM5 Chip can bind Cynomolgus HLA-G Complex Tetramer, His Tag with an affinity constant of 852 nM as determined in SPR assay (Biacore T200).
	Cynomolgus LILRB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus LILRB2 is greater than 95% as determined by SEC-HPLC.