Name: Cynomolgus LILRB2/CD85d/ILT4 Protein (LIL-CM1B2)
Brand: KactusBio
SKU: LIL-CM1B2-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus LILRB2/CD85d/ILT4 Protein (LIL-CM1B2)

Cynomolgus LILRB2, His Tag immobilized on CM5 Chip can bind Cynomolgus HLA-G Complex Tetramer, His Tag with an affinity constant of 852 nM as determined in SPR assay (Biacore T200).

Cynomolgus LILRB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus LILRB2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 852 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly24-Arg457

Catalog #LIL-CM1B2

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus LILRB2/CD85d/ILT4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly24-Arg457.
Product Background	The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	LILRB2/CD85d/ILT4
Synonyms	CD85d; ILT4; ILT-4; ILT4CD85d; LILRB2; LIR2; MIR10
Accession	XP_015297203.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gly24-Arg457
Molecular Weight	The protein has a predicted MW of 48.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 852 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus LILRB2, His Tag immobilized on CM5 Chip can bind Cynomolgus HLA-G Complex Tetramer, His Tag with an affinity constant of 852 nM as determined in SPR assay (Biacore T200).
	Cynomolgus LILRB2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus LILRB2 is greater than 95% as determined by SEC-HPLC.