Product Description |
Recombinant Cynomolgus/Rhesus macaque LRRC15/LIB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr22-Gly538. |
Product Background |
The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.- LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
LRRC15/LIB |
Synonyms |
LIB; LRRC15; EGM_11224 |
Accession |
|
Species |
Cynomolgus/Rhesus macaque |
Biotinylated |
no |
Amino Acid Range |
Tyr22-Gly538 |
Molecular Weight |
The protein has a predicted MW of 58.92 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Anti-LRRC15 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus LRRC15, His Tag with the EC50 of 15.3ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Anti-LRRC15 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus LRRC15, His Tag with the EC50 of 15.3ng/ml determined by ELISA (QC Test). |
|
|
Cynomolgus/Rhesus macaque LRRC15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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