Cynomolgus MSLN/Mesothelin Protein (MSL-CM281)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus MSLN, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Asp296-Ser598

Catalog: MSL-CM281

$315.00
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Product Description Recombinant Cynomolgus MSLN/Mesothelin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asp296-Ser598.

Product Background

Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.

Product Category

Recombinant Protein

Target

MSLN/Mesothelin

Gene/Protein ID

XP_005590873.3

Species

Cynomolgus

Exact Sequence

Asp296-Ser598
Molecular Weight The protein has a predicted MW of 34.87 kDa. Due to glycosylation, the protein migrates to 43-53 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus MSLN, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus MSLN, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 1.3ng/ml determined by ELISA.
The purity of Cynomolgus MSLN is greater than 95% as determined by SEC-HPLC.
Cynomolgus MSLN on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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