Product Description |
Recombinant Cynomolgus ROR2/NTRKR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu34-Met402. |
Product Background |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. |
Product Category |
Recombinant Protein / Antibody discovery |
Protein |
ROR2/NTRKR2 |
Synonyms |
BDB; BDB1; NTRKR2; ROR2 |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Glu34-Met402 |
Molecular Weight |
The protein has a predicted MW of 42.29 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus ROR2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Cynomolgus ROR2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. |
|
|
Cynomolgus ROR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Cynomolgus ROR2 is greater than 95% as determined by SEC-HPLC. |
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