Cynomolgus Siglec-3/CD33 Protein (CD3-CM133)
Cynomolgus Siglec-3/CD33 Protein (CD3-CM133)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser17-Leu248
Catalog #CD3-CM133
Regular price $315.00
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Product Description
Recombinant Cynomolgus Siglec-3/CD33 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser17-Leu248.
Product Background
Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.
Product Category
Recombinant Protein
Target
Siglec-3/CD33
Synonyms
CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Ser17-Leu248
Molecular Weight
The protein has a predicted MW of 26.83 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Cynomolgus Siglec-3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus Siglec-3 is greater than 95% as determined by SEC-HPLC.

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