Cynomolgus TIM-1/HAVCR1 Protein (TIM-CM101)
Cynomolgus TIM-1/HAVCR1 Protein (TIM-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Val23-Gly342
Catalog #TIM-CM101
Regular price $315.00
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Product Description
Recombinant Cynomolgus TIM-1/HAVCR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val23-Gly342.
Product Background
Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation.
Product Category
Recombinant Protein
Target
TIM-1/HAVCR1
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Val23-Gly342
Molecular Weight
The protein has a predicted MW of 35.25 kDa. Due to glycosylation, the protein migrates to 100-150 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Cynomolgus TIM-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus TIM-1 is greater than 95% as determined by SEC-HPLC.

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