Name: Cynomolgus TYRO3 Protein (TYR-CM103)
Brand: KactusBio
SKU: TYR-CM103-100UG
Price: 315.0 USD
Availability: InStock

Catalog #TYR-CM103

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus TYRO3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly41-Ser427.
Product Background	The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew macrophage polarization towards a pro-tumor M2-like phenotype.In macrophages, the TAM receptors also promote apoptotic cell clearance, a tumor-promoting process called efferocytosis. The TAM receptors bind the "eat-me" signal phosphatidylserine on apoptotic cell membranes using Gas6 and Protein S as bridging ligands.
Product Category	Recombinant Protein / Antibody discovery

Protein	TYRO3
Synonyms	BYK; DTK; RSE; SKY; TIF; TYRO3; Brt; Rse
Accession	A0A2K5WCY8
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gly41-Ser427
Molecular Weight	The protein has a predicted MW of 42.47 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by SEC-HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus TYRO3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus TYRO3 is greater than 95% as determined by SEC-HPLC.