Product Description |
Recombinant FITC-Labeled Human B7-H3/CD276 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu29-Pro245. |
Product Background |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets |
Protein |
B7-H3/CD276 |
Synonyms |
B7H3; B7-H3; CD276; PSEC0249;-UNQ309; PRO352; B7 homolog 3; CD276 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu29-Pro245 |
Molecular Weight |
The protein has a predicted MW of 50.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
FITC-Labeled Human B7-H3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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