SDS-PAGE image showing protein purity and molecular weight estimation of recombinant protein.
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Leu29-Pro245
Catalog #BH7-HM273F
Regular price $990.00
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Product Description

Recombinant FITC-Labeled Human B7-H3/CD276 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu29-Pro245.

Product Background

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets
Protein
B7-H3/CD276
Synonyms
B7H3; B7-H3; CD276; PSEC0249;-UNQ309; PRO352; B7 homolog 3; CD276
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Leu29-Pro245
Molecular Weight
The protein has a predicted MW of 50.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
FITC-Labeled Human B7-H3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. FITC-Labeled Human B7-H3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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