FITC-Labeled Human B7-H3/CD276 Protein (BH7-HM273F)
Catalog: BH7-HM273F
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| Product Description | Recombinant FITC-Labeled Human B7-H3/CD276 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu29-Pro245. |
Product Background |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. |
Product Category |
Recombinant Protein |
Target |
B7-H3/CD276 |
Gene/Protein ID |
Q5ZPR3-2 |
Species |
Human |
Exact Sequence |
Leu29-Pro245 |
| Molecular Weight | The protein has a predicted MW of 50.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-hFc |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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FITC-Labeled Human B7-H3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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