FITC-Labeled Human CDH17/Cadherin 17 Protein (CDH-HM117F)
FITC-Labeled Human CDH17/Cadherin 17 Protein (CDH-HM117F)
FITC-Labeled Human CDH17/Cadherin 17 Protein (CDH-HM117F)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized FITC-Labeled Human CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln23-Met787
Catalog #CDH-HM117F
Regular price $990.00
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Product Description

Recombinant FITC-Labeled Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Met787.

Product Background

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

CDH17/Cadherin 17

Synonyms

Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gln23-Met787

Molecular Weight

The protein has a predicted MW of 86.1 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result.

Activity

Immobilized FITC-Labeled Human CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized FITC-Labeled Human CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. Immobilized FITC-Labeled Human CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.
FITC-Labeled Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. FITC-Labeled Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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