FITC-Labeled Human FOLR1 Protein (FOL-HM4R1F)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized FITC-Labeled Human FOLR1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FOLR1 Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Arg25-Met233
Catalog #FOL-HM4R1F
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Product Description
 Recombinant FITC-Labeled Human FOLR1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Arg25-Met233.
Product Background
 Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH.
Product Category
 Recombinant Protein
Target
 FOLR1
Synonyms
 FR-alpha; FR alpha; FR α; FOLR; FOLR1; FBP; Folbp1; KB cells FBP; MOv18; Folate receptor 1; Fbp1; Folate receptor alpha;
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Arg25-Met233
Molecular Weight
 The protein has a predicted MW of 27.5 kDa. Due to glycosylation, the protein migrates to 37-47 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized FITC-Labeled Human FOLR1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FOLR1 Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA. See testing image for detail.
Product Tag
 C-His-Avi
Express System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized FITC-Labeled Human FOLR1, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-FOLR1 Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA.
FITC-Labeled Human FOLR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of FITC-Labeled Human FOLR1 is greater than 95% as determined by SEC-HPLC.

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