Name: Human 2B4/CD244/SLAMF4 Protein (2B4-HM201)
Brand: KactusBio
SKU: 2B4-HM201-100UG
Price: 223.3 USD
Availability: InStock

Human 2B4/CD244/SLAMF4 Protein (2B4-HM201)

Immobilized Human CD48, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA.

Human 2B4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human 2B4 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD48, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Cys22-Arg221

Catalog #2B4-HM201

Size

100UG

500UG

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Product Description	Recombinant Human 2B4/CD244/SLAMF4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Cys22-Arg221.
Product Background	2B4 (CD244) is expressed by memory-phenotype CD8(+) T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	2B4/CD244/SLAMF4
Synonyms	2B4; CD244 antigen; CD244; h2B4; NAIL; NKR2B4; Nmrk; SLAMF4
Accession	Q9BZW8-2
Species	Human
Biotinylated	no
Amino Acid Range	Cys22-Arg221
Molecular Weight	The protein has a predicted MW of 49 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD48, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD48, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 0.13ug/ml determined by ELISA.
	Human 2B4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human 2B4 is greater than 95% as determined by SEC-HPLC.