Human ANXA1 Protein (ANX-HE1A1)
Catalog: ANX-HE1A1
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| Product Description | Recombinant Human ANXA1 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Met1-Asn346. |
Product Background |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. |
Product Category |
Recombinant Protein |
Target |
ANXA1 |
| Synonyms | Annexin I; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; p35; ANX1; LPC1; Annexin A1; Annexin-1; ANXA1 |
Gene/Protein ID |
P04083 |
Species |
Human |
Exact Sequence |
Met1-Asn346 |
| Molecular Weight | The protein has a predicted MW of 39.5 kDa same as Tris-Bis PAGE result. |
Product Tag |
C-His |
Express System |
E.coli |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Human ANXA1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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