Human ANXA1 Protein (ANX-HE1A1)
  • Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Met1-Asn346
Catalog #ANX-HE1A1
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Product Description
 Recombinant Human ANXA1 Protein is expressed from E.coli with His tag at the C-terminus.It contains Met1-Asn346.
Product Background
 Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance.
Product Category
 Recombinant Protein
Target
 ANXA1
Synonyms
 Annexin I; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; p35; ANX1; LPC1; Annexin A1; Annexin-1; ANXA1
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Asn346
Molecular Weight
 The protein has a predicted MW of 39.5 kDa same as Bis-Tris PAGE result.
Product Tag
 C-His
Express System
 E.coli
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human ANXA1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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