Name: Human AXL Protein (AXL-HM201)
Brand: KactusBio
SKU: AXL-HM201-100UG
Price: 297.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GAS6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human AXL, hFc Tag with the EC50 of 3.4 ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala26-Pro449

Catalog #AXL-HM201

Size

100UG

500UG

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Product Description	Recombinant Human AXL Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ala26-Pro449.
Product Background	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
Product Category	Recombinant Protein / Antibody discovery

Protein	Axl
Synonyms	Axl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1
Accession	P30530-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala26-Pro449
Molecular Weight	The protein has a predicted MW of 72.6 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GAS6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human AXL, hFc Tag with the EC50 of 3.4 ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GAS6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human AXL, hFc Tag with the EC50 of 3.4 ng/ml determined by ELISA.
	Human AXL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human AXL is greater than 95% as determined by SEC-HPLC.