Human BTN3A2 Protein (BNT-HM2A2) Summary
Product Description |
Recombinant Human BTN3A2 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Gln30-Trp248. |
Product Background |
BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a potential prognostic biomarker for the identification of HG-EOC patients with better outcome. In contrast, high CD206 /CD68 expression is associated with high risk of disease progression. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human BTN3A2 Protein (BNT-HM2A2) Specifications/Details
Protein |
BTN3A2 |
Synonyms |
BT3.2; BTF3; BTF4; BT3.3; BTN3A2; FLJ40011; BTN3.2; CD277 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln30-Trp248 |
Molecular Weight |
The protein has a predicted MW of 50.37 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
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Human BTN3A2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human BTN3A2 is greater than 95% as determined by SEC-HPLC. |
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