Name: Human CA125/MUC16 Protein (MUC-HM126)
Brand: KactusBio
SKU: MUC-HM126-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human CA125, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 7.8 ng/ml determined by ELISA.
Amino Acid Range: Asp12783-Ser13467

Catalog #MUC-HM126

Size

100UG

500UG

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Human CA125/MUC16 Protein (MUC-HM126) Summary

Product Description	Recombinant Human CA125/MUC16 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp12783-Ser13467.
Product Background	MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets \| ADC targets

Human CA125/MUC16 Protein (MUC-HM126) Specifications/Details

Protein	CA125/MUC16
Synonyms	CA125; CA-125; CA125MUC-16; FLJ14303; MUC16
Accession	Q8WXI7
Species	Human
Biotinylated	no
Amino Acid Range	Asp12783-Ser13467
Molecular Weight	The protein has a predicted MW of 76.17 kDa. Due to glycosylation, the protein migrates to 90-140 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CA125, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 7.8 ng/ml determined by ELISA.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CA125, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 7.8 ng/ml determined by ELISA.
	Human CA125 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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