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Human CD27 Ligand/CD70 Protein (CD7-HM270) Summary
Product Description |
Recombinant Human CD27 Ligand/CD70 Protein is expressed from HEK293 with hFc (IgG1) at the N-Terminus.It contains Gln39-Pro193. |
Product Background |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.- CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets, ADC targets |
Human CD27 Ligand/CD70 Protein (CD7-HM270) Specifications/Details
Protein |
CD27 Ligand/CD70 |
Synonyms |
CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG;-Ki-24 antigen; TNFSF7G |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln39-Pro193 |
Molecular Weight |
The protein has a predicted MW of 42.7 kDa. Due to glycosylation, the protein migrates to 75-90 kDa under Non reduced (N) condition based on Bis-Tris PAGE result. |
Activity |
Immobilized Human CD27, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human CD27 Ligand, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA. |
Product Tag |
N-hFc (IgG1) |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Human CD27, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human CD27 Ligand, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA. |
|
|
Human CD27 Ligand on Bis-Tris PAGE under Non reduced (N) condition. The purity is greater than 95%. |
Other Available Proteins:
Finding available proteins...
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