Name: Human CD37 Protein (CD3-HM237)
Brand: KactusBio
SKU: CD3-HM237-100UG
Price: 297.0 USD
Availability: InStock

Catalog #CD3-HM237

Size

100UG

500UG

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Human CD37 Protein (CD3-HM237) Summary

Product Description	Recombinant Human CD37 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Ala113-Asn240.
Product Background	CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Human CD37 Protein (CD3-HM237) Specifications/Details

Protein	CD37
Synonyms	Tetraspanin-26; Tspan-26; CD37; CD37 molecule; GP52-40; MGC120234
Accession	P11049-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala113-Asn240
Molecular Weight	The protein has a predicted MW of 41.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Product Tag	N-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human CD37 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CD37 is greater than 95% as determined by SEC-HPLC.

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