Name: Human CD48/SLAMF2 Protein (SLA-HM148)
Brand: KactusBio
SKU: SLA-HM148-100UG
Price: 280.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD48, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 89.8ng/ml determined by ELISA.
Amino Acid Range: Gln27-Ser220

Catalog #SLA-HM148

Size

100UG

500UG

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Human CD48/SLAMF2 Protein (SLA-HM148) Summary

Product Description	Recombinant Human CD48/SLAMF2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln27-Ser220.
Product Background	CD48, also known as BLAST-1, BCM-1, and SLAMF2, is a 65 kDa GPI-linked protein in the CD2 family of immunoglobulin superfamily molecules.CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins \| ADC targets

Human CD48/SLAMF2 Protein (SLA-HM148) Specifications/Details

Protein	CD48/SLAMF2
Synonyms	CD48 molecule; CD48; SLAMF2; BCM1; BLAST; BLAST1; BLAST1TCT.1;- mCD48; MEM-102; TCT.1
Accession	P09326-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln27-Ser220
Molecular Weight	The protein has a predicted MW of 23.4 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD48, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 89.8ng/ml determined by ELISA.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CD48, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human 2B4, hFc Tag with the EC50 of 89.8ng/ml determined by ELISA.
	Human CD48 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human CD48, His Tag on Anti-His-Biosensor can bind Human 2B4, hFc Tag with an affinity constant of 5.79 nM as determined in BLI assay .
	The purity of Human CD48 is greater than 95% as determined by SEC-HPLC.

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