Name: Human CDH17/Cadherin 17 Domain 5-7 Protein (CDH-HM1D4)
Brand: KactusBio
SKU: CDH-HM1D4-100UG
Price: 390.0 USD
Availability: InStock

Human CDH17/Cadherin 17 Domain 5-7 Protein (CDH-HM1D4)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Amino Acid Range: Glu450-Gly777

Catalog #CDH-HM1D4

Size

100UG

500UG

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Product Description	Recombinant Human CDH17/Cadherin 17 Domain 5-7 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu450-Gly777.
Product Background	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Product Category	Recombinant Protein

Target	CDH17/Cadherin 17 Domain 5-7
Synonyms	Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024
Accession	Q12864
Species	Human
Biotinylated	no
Amino Acid Range	Glu450-Gly777
Molecular Weight	The protein has a predicted MW of 36.79 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Human CDH17 Domain 5-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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