Human CEACAM-5/CD66e (145-322) Protein (CAM-HM1D1)
Human CEACAM-5/CD66e (145-322) Protein (CAM-HM1D1)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
  • Amino Acid Range: Pro145-Pro322
Catalog #CAM-HM1D1
Regular price $345.00
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Product Description
Recombinant Human CEACAM-5/CD66e (145-322) Protein is expressed from HEK293 with His tag at the C-terminus; It contains Pro145-Pro322.
Product Background
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.
Product Category
Recombinant Protein
Target
CEACAM-5/CD66e (145-322)
Synonyms
CEACAM-5; CD66e; CEA; Carcinoembryonic; CEACD66e
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Pro145-Pro322
Molecular Weight
The protein has a predicted MW of 20.66 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human CEACAM-5 (145-322) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CEACAM-5 (145-322) is greater than 95% as determined by SEC-HPLC.

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