Human CEACAM-5/CD66e (145-322) Protein (CAM-HM1D1)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
  • Exact Sequence: Pro145-Pro322

Catalog: CAM-HM1D1

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Product Description Recombinant Human CEACAM-5/CD66e (145-322) Protein is expressed from HEK293 with His tag at the C-terminus.; It contains Pro145-Pro322.

Product Background

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Product Category

Recombinant Protein

Target

CEACAM-5/CD66e (145-322)

Gene/Protein ID

P06731-1

Species

Human

Exact Sequence

Pro145-Pro322
Molecular Weight The protein has a predicted MW of 20.66 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Less than 1 EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human CEACAM-5 (145-322) is greater than 95% as determined by SEC-HPLC.
Human CEACAM-5 (145-322) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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