Name: Human CEACAM-5/CD66e (145-322) Protein (CAM-HM1D1)
Brand: KactusBio
SKU: CAM-HM1D1-100UG
Price: 345.0 USD
Availability: InStock

Human CEACAM-5/CD66e (145-322) Protein (CAM-HM1D1)

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Amino Acid Range: Pro145-Pro322

Catalog #CAM-HM1D1

Size

100UG

500UG

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Product Description	Recombinant Human CEACAM-5/CD66e (145-322) Protein is expressed from HEK293 with His tag at the C-terminus; It contains Pro145-Pro322.
Product Background	Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.
Product Category	Recombinant Protein

Target	CEACAM-5/CD66e (145-322)
Synonyms	CEACAM-5; CD66e; CEA; Carcinoembryonic; CEACD66e
Accession	P06731-1
Species	Human
Biotinylated	no
Amino Acid Range	Pro145-Pro322
Molecular Weight	The protein has a predicted MW of 20.66 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Express System	HEK293
Purity	>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human CEACAM-5 (145-322) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CEACAM-5 (145-322) is greater than 95% as determined by SEC-HPLC.

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