Human CEACAM-5/CD66e Protein (CAM-HM105)
Human CEACAM-5/CD66e Protein (CAM-HM105)
Human CEACAM-5/CD66e Protein (CAM-HM105)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE; >95% as determined by HPLC
  • Activity: Immobilized Human CEACAM-5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-CEACAM5 Antibody, hFc Tag with the EC50 of 5.6 ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Lys35-Ala685
Catalog #CAM-HM105
Regular price $225.00
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Product Description

Recombinant Human CEACAM-5/CD66e Protein is expressed from HEK293 with His tag at the C-terminus; It contains Lys35-Ala685.

Product Background

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets

Protein

CEACAM-5/CD66e

Synonyms

CEACAM-5; CD66e; CEA; Meconium antigen 100; Carcinoembryonic; CEACD66e; DKFZp781M2392

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Lys35-Ala685

Molecular Weight

The protein has a predicted MW of 72.42 kDa. Due to glycosylation, the protein migrates to 100-140 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human CEACAM-5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-CEACAM5 Antibody, hFc Tag with the EC50 of 5.6 ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

>95% as determined by Bis-Tris PAGE; >95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CEACAM-5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-CEACAM5 Antibody, hFc Tag with the EC50 of 5.6 ng/ml determined by ELISA (QC Test). Immobilized Human CEACAM-5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-CEACAM5 Antibody, hFc Tag with the EC50 of 5.6 ng/ml determined by ELISA (QC Test).
Human CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human CEACAM-5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human CEACAM-5 is greater than 95% as determined by SEC-HPLC. The purity of Human CEACAM-5 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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