Human Claudin 18.2 Protein-VLP (CLD-HE1822)

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Human Claudin 18.2 VLP at 5 ug/ml (100 ul/Well). Dose response curve for Anti-Claudin 18.2 Antibody, hFc Tag with the EC50 of 9.8 ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Met1-Val261

Catalog: CLD-HE1822

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Product Description	Full length Human Claudin 18.2 Protein-VLP is expressed from HEK293. It contains Met1-Val261.
Product Background	Claudin18 (CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
Product Category	Recombinant Protein

Target	Claudin 18.2
Synonyms	CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Accession	P56856-2
Species	Human
Amino Acid Range	Met1-Val261
Molecular Weight	The target protein has a predicted MW of 29 kDa.
Activity	Immobilized Human Claudin 18.2 VLP at 5 ug/ml (100 ul/Well). Dose response curve for Anti-Claudin 18.2 Antibody, hFc Tag with the EC50 of 9.8 ng/ml determined by ELISA (QC Test). See testing image for detail.
Express System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 300 mM L-Arginine (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Claudin 18.2 VLP at 5 ug/ml (100 ul/Well). Dose response curve for Anti-Claudin 18.2 Antibody, hFc Tag with the EC50 of 9.8 ng/ml determined by ELISA (QC Test).
	The purity of Human Claudin 18.2 VLP is greater than 95% as determined by SEC-HPLC.