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Human/Cynomolgus/Rhesus macaque ROR1 (30-305,Ig-like&Frizzled Domain) Protein (ROR-HM1IF) Summary
Product Description |
Recombinant Human/Cynomolgus/Rhesus macaque ROR1 (30-305,Ig-like&Frizzled Domain) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln30-Asp305. |
Product Background |
ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1),- is a member of- the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members. |
Product Category |
Recombinant Protein / Antibody discovery / CAR-T targets | ADC targets |
Human/Cynomolgus/Rhesus macaque ROR1 (30-305,Ig-like&Frizzled Domain) Protein (ROR-HM1IF) Specifications/Details
Protein |
ROR1 |
Synonyms |
ROR1; NTRKR1; dJ537F10.1 |
Accession |
|
Species |
Human/Cynomolgus/Rhesus macaque |
Biotinylated |
no |
Amino Acid Range |
Gln30-Asp305 |
Molecular Weight |
The protein has a predicted MW of 31.90 kDa. Due to glycosylation, the protein migrates to 48-53 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human/Cynomolgus/Rhesus macaque ROR1 (30-305,Ig-like&Frizzled Domain), His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ROR1 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized Human/Cynomolgus/Rhesus macaque ROR1 (30-305,Ig-like&Frizzled Domain), His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-ROR1 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. |
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Human/Cynomolgus/Rhesus macaque ROR1 (30-305,Ig-like&Frizzled Domain) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human/Cynomolgus/Rhesus macaque ROR1 (30-305,Ig-like&Frizzled Domain) is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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