Human/Cynomolgus/Rhesus macaque ROR1 Protein (ROR-HM201)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human/Cynomolgus/Rhesus macaque ROR1, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ROR1 Antibody, hFc Tag with the EC50 of 13.4ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln30-Glu403

Catalog: ROR-HM201

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Product Description Recombinant Human/Cynomolgus/Rhesus macaque ROR1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln30-Glu403.

Product Background

ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1),- is a member of- the ROR family within receptor tyrosine kinases (RTK) superfamily. Two ROR family members (ROR1 and ROR2) have been identified and are characterized by the intracellular tyrosine kinase domains, highly related to those of the Trk-family receptor tyrosine kinases, and by the extracellular Frizzled-like cysteine-rich domains and kringle domains, which are common to receptors of the Wnt family members.

Product Category

Recombinant Protein

Target

ROR1
Synonyms ROR1; NTRKR1; dJ537F10.1
Accession

Species

Human/Cynomolgus/Rhesus macaque

Amino Acid Range

Gln30-Glu403
Molecular Weight The protein has a predicted MW of 68.8 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human/Cynomolgus/Rhesus macaque ROR1, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ROR1 Antibody, hFc Tag with the EC50 of 13.4ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human/Cynomolgus/Rhesus macaque ROR1, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-ROR1 Antibody, hFc Tag with the EC50 of 13.4ng/ml determined by ELISA.
The purity of Human/Cynomolgus/Rhesus macaque ROR1 is greater than 95% as determined by SEC-HPLC.
Human/Cynomolgus/Rhesus macaque ROR1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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