Human DLL3 Domain (352-479) Protein (DLL-HM4D2)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: >95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Lys352-Ala479
Catalog #DLL-HM4D2
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Product Description
 Recombinant Human DLL3 Domain (352-479) Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.; It contains Lys352-Ala479.
Product Background
 Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
Product Category
 Recombinant Protein
Target
 DLL3 Domain (352-479)
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Lys352-Ala479
Molecular Weight
 The protein has a predicted MW of 17.30 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi
Express System
 HEK293
Purity
 >95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.
Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
 Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human DLL3 Domain (352-479) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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