Name: Human DSG-2/Desmoglein-2 Protein (DSG-HM102)
Brand: KactusBio
SKU: DSG-HM102-100UG
Price: 270.0 USD
Availability: InStock

Human DSG-2/Desmoglein-2 Protein (DSG-HM102)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human DSG-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala50-Gly609

Catalog #DSG-HM102

Size

100UG

500UG

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Product Description	Recombinant Human DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.
Product Background	Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
Product Category	Recombinant Protein

Target	DSG-2/Desmoglein-2
Synonyms	Desmoglein-2; HDGC; DSG2; CDHF5; ARVC10; CMD1BB; MGC117036; MGC117037
Accession	Q14126
Species	Human
Biotinylated	no
Amino Acid Range	Ala50-Gly609
Molecular Weight	The protein has a predicted MW of 63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human DSG-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human DSG-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 18.2ng/ml determined by ELISA.
	Human DSG-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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